In the last column, we talked about adverse effects, presented in a recently published review in The New England Journal of Medicine.
We explain that studies in this area suffer from methodological problems. They usually involve users who consume larger amounts for many years, packaged based on varying concentrations of tetrahydrocannabinol (THC), the active ingredient.
As a consequence, the undesirable consequences for occasional users, the large mass of consumers, are unclear.
By contrast, the medicinal use of THC and its other cannabinoids is abundantly documented.
The discovery that cannabinoids bound to CB receptors on the cell membrane of neurons came in 1988. Two years later, these receptors were cloned and mapped their locations in the brain. In 1992, anandamide, a receptor-related but distinct substance in the central nervous system, was identified.
Since then, several studies have revealed that natural or synthetic cannabinoids play an important role in pain modulation, movement control, memory formation and archiving and even in the immune response.
Research on laboratory animals has shown that the brain develops tolerance to cannabinoids and that they can cause addiction, although this potential is lower than that of heroin, nicotine, cocaine, alcohol and benzodiazepines such as diazepam.
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We explain that studies in this area suffer from methodological problems. They usually involve users who consume larger amounts for many years, packaged based on varying concentrations of tetrahydrocannabinol (THC), the active ingredient.
As a consequence, the undesirable consequences for occasional users, the large mass of consumers, are unclear.
By contrast, the medicinal use of THC and its other cannabinoids is abundantly documented.
The discovery that cannabinoids bound to CB receptors on the cell membrane of neurons came in 1988. Two years later, these receptors were cloned and mapped their locations in the brain. In 1992, anandamide, a receptor-related but distinct substance in the central nervous system, was identified.
Since then, several studies have revealed that natural or synthetic cannabinoids play an important role in pain modulation, movement control, memory formation and archiving and even in the immune response.
Research on laboratory animals has shown that the brain develops tolerance to cannabinoids and that they can cause addiction, although this potential is lower than that of heroin, nicotine, cocaine, alcohol and benzodiazepines such as diazepam.
https://www.deviantart.com/marijuna54
http://www.abstractfonts.com/members/664238
https://www.theverge.com/users/marijuna353
https://www.steinberg.net/forums/memberlist.php?mode=viewprofile&u=159381
https://www.plerb.com/medical758
https://ask.fm/onlinedespansary
https://myspace.com/medical076
http://ecoups.net/groups/hvac-advice-you-want-to-have-right-now-advice-number-35-of-508/
https://knowyourmeme.com/users/kamiya-cena
https://500px.com/onlinedespansary
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